Are there any potential side effects from taking supra-high doses of resveratrol?

Yes. First, resveratrol is a copper chelator and copper is needed for production of collagen. Users of very high-dose (~500-2500 mg) resveratrol now commonly report Achilles heel tendonitis. Collagen may be compromised elsewhere in the body as well.

Another drawback of super-high doses of Longevinex may be iron-deficiency. Cold fingertips and toes accompanied by fatigue, pale skin and craving for acidic foods (tomatoes) may be signs of an iron shortage.

There are potential problems taking Longevinex with prescription medications. Some of the ingredients in Longevinex® may inhibit the activity of detoxification enzymes in the liver. A similar effect is produced by consumption of grapefruit juice with medications. This can result in medications working too well, producing side effects. For example, a person taking blood pressure-lowering drugs may find their blood pressure drops too low, producing temporary dizziness. It is best to take Longevinex at a different time from any medications.

A few people report easier skin bruising when taking Longevinex. The ingredients in Longevinex have a blood-thinning effect. Many consumers take up to 5 capsules a day of Longevinex without experiencing blood-thinning effects.

Some people taking resveratrol supplements report loose stool. This emanates from the emodin content in resveratrol supplements derived from Giant Knotweed. Longevinex is now virtually emodin free.

The ingredients in Longevinex help to reduce abnormally high levels of inflammatory agents, like TNF (tumor necrosis factor). TNF is a normal part of the human immune system. It helps to control bacterial and viral infection. With advancing years and the accumulation of metallic metals in the body, such as iron, copper, manganese, aluminum, too much TNF is produced which results in uncontrolled inflammation. The metal-chelating TNF inhibitors in Longevinex serve to reduce inflammation by limitation or removal of these metals.

However, excessive dosing of Longevinex may reduce TNF to sub-par levels and impair the immune response. If taking Longevinex and you develop a skin rash, stiff joints or flu-like symptoms, cease use and report this occurrence to Longevinex at 866 405-4000 or (include your phone number).
Any side effect believed to be associated with Longevinex which requires a doctor visit should be reported.