The dose of resveratrol and total ingredients in Longevinex has been carefully calculated to mimic the effect of three to five glasses of dark red wine to produce an optimal biological effect for a 160-pound adult. More is not better and may negate the positive benefits altogether. It is also important not to take too many other herbal supplements in the same class as resveratrol, such as curcumin, green tea, grape seed, milk thistle, etc.